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All Products in Alphabetical Listing

Alkanethiols and Dialkyl Disulfides and Educational Kits.  If you do not find a specific compound, please contact us to discuss further options.

Educational Kits

Our first educational kit demonstrates a commonly used technique in nanotechnology, the formation of a self-assembled monolayer, in an easily visible manner.  This is a fun lab exercise for middle school through high school and freshmen level students and a great demo for more advanced students to introduce the concept of nanotechnology.

Biological Applications

Head groups in this category have shown their usefulness in biological applications.  Head groups include functionalities that aid in certain responses, such as specific cell or protein adhesion, or prevent responses, such as non-specific protein adsorption.  Compounds that have been used as negative controls have also been included in this category. 

Non-Fouling Compounds (PEG Thiols)

These compounds have been well documented in literature as those that form non-fouling surfaces.  This means that non-specific protein adsorption is minimized or zero compared to other functional groups.  The degree of non-fouling is also significantly influenced by the preparation method as well as by the sensitivity of the analytical method used.

Reactive and Derivatizable Compounds

This category includes head groups that are reactive towards other functional groups.  Some of them are specifically designed or have well established documentation for surface reactions performed on monolayers.  These can be highly useful in patterning and attaching large groups that would be otherwise difficult to be incorporate into a SAM, such as proteins, cells, and DNA.

Electronically Active Compounds

These alkanethiol compounds contain headgroups and/or spacer groups that can conduct electrons or change their electrical properties under the proper conditions. These types of molecules are important for studies in the area of molecular electronics and electrically active sensors.

Filler Molecules

These simple alkanethiols and dialkyl disulfides, as well as PEG thiols, have been used as filler molecules in mixed monolayers.  They give a background that is neutral to the specific application and help space the compound or head group of interest.  The type of compound used as filler depends on the purpose of the experiment.  When preparing mixed monolayers one should keep in mind that the solution concentration hardly ever corresponds to the resulting surface concentration, since the adsorption kinetics of the two compounds making up the mixed monolayer will be different depending on chain length, functional group and oxidation state of the sulfur (thiol vs. disulfide).

Instrument Standard

These compounds are well suited for tuning and calibrating common surface analytical instrumentation, such as XPS, ATR, IRRAS, and TOF-SIMs, due to a unique element in the molecule, such as fluorine or deuterium.  In addition, some of these give favorable backgrounds for techniques such as SPR and IR.

Hydrophilic

The head group of these compounds will form monolayers that are highly wetting or hydrophilic.  These include mostly polar groups that interact well with water.  These compounds are also commonly used as filler molecules in mixed monolayers when a hydrophilic background is necessary.

Hydrophobic

These functional groups are well documented as giving highly hydrophobic monolayers - meaning that a water droplet will bead up when placed on the surface.  Most of these compounds are also useful in mixed monolayers when a hydrophobic filler molecule is desirable.